Sourdough Pesto Grilled Cheese

Featured in: Everyday Family Meals

Transform your lunch with this gourmet grilled cheese that elevates the classic comfort food. Thick-cut sourdough bread is layered with aromatic basil pesto and a carefully chosen blend of mozzarella, fontina, and sharp white cheddar cheese.

The preparation is straightforward: butter the bread, spread pesto on the inner sides, add your cheese blend, and grill until golden. The entire sandwich comes together in just 20 minutes, making it perfect for a quick meal that feels indulgent.

Customize your creation by adding fresh tomato slices or spinach, or swap cheeses to suit your preferences. Serve alongside a crisp salad or warm tomato soup for a satisfying meal.

Updated on Tue, 20 Jan 2026 10:24:00 GMT
Golden-brown Sourdough Pesto Grilled Cheese sandwich oozing melted mozzarella and fontina, served on a rustic wooden board. Save to Pinterest
Golden-brown Sourdough Pesto Grilled Cheese sandwich oozing melted mozzarella and fontina, served on a rustic wooden board. | recipesbies.com

The smell of pesto hitting warm bread takes me back to my first apartment, where the kitchen was barely big enough to turn around in but somehow produced the best meals. I'd been experimenting with grilled cheese variations for months, trying to elevate something simple into something memorable without overcomplicating it. That afternoon when I smeared bright green basil pesto across sourdough and watched it bubble up with three cheeses, I knew I'd stumbled onto something special. My roommate walked in and immediately asked for a bite, then demanded I make it for dinner that same night.

Last winter my friend texted me at 11 PM saying she'd had the worst day and needed something comforting. I doubled this recipe and we sat on her couch with tomato soup eating these sandwiches while watching terrible movies and laughing about nothing. She still texts me every time she makes them now saying it fixed whatever went wrong that week.

Ingredients

  • 4 slices thickcut sourdough bread: The sturdy texture holds up beautifully to all that cheese while developing an incredible crunch when buttered and griddled
  • 1/2 cup shredded mozzarella cheese: Provides that classic stretch and mild milky flavor that forms the perfect base for the other cheeses
  • 1/2 cup shredded fontina cheese: This is the secret weapon with its nutty buttery flavor and superior melting qualities
  • 1/2 cup shredded sharp white cheddar: Adds just enough tang and complexity to keep the sandwich from becoming one note
  • 3 tbsp basil pesto: Storebought works perfectly fine but homemade brings such incredible aromatic freshness that transforms the whole sandwich
  • 2 tbsp unsalted butter softened: Spreads easily and creates that gorgeous golden exterior that makes grilled cheese so irresistible

Instructions

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Prep your bread slices:
Lay out all four slices and spread half a tablespoon of softened butter on one side of each piece getting all the way to the edges for maximum golden crunch
Add the flavor foundation:
Flip the bread over so the unbuttered side faces up then spread about a tablespoon of pesto across two slices making sure every bite will have that basil goodness
Layer on the cheese:
Evenly distribute the mozzarella fontina and cheddar over the pesto covered slices right to the edges so nothing escapes when it melts
Assemble the sandwiches:
Top each cheese pile with the remaining bread slices buttered side facing out like youre creating the perfect golden seal
Get your pan ready:
Heat a large nonstick skillet over medium heat until a drop of water sizzles across the surface telling you its perfectly primed
Grill to perfection:
Carefully place both sandwiches in the pan and cook for 3 to 4 minutes per side pressing gently with your spatula until golden brown and crisp with cheese completely melted
Let them rest briefly:
Remove from the pan and let sit for just one minute before slicing so the cheese sets slightly instead of pouring out everywhere
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Perfect for simmering soups, baking casseroles, and serving cozy one-pot meals straight from oven to table.
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Close-up of crispy Sourdough Pesto Grilled Cheese, revealing vibrant basil pesto and sharp cheddar between thick slices. Save to Pinterest
Close-up of crispy Sourdough Pesto Grilled Cheese, revealing vibrant basil pesto and sharp cheddar between thick slices. | recipesbies.com

My dad who swears by his basic American cheese grilled cheese was skeptical until he tried this version on a Sunday afternoon. He took one bite closed his eyes and said I might never go back to the original again.

Choosing The Right Cheese Blend

Ive tested countless cheese combinations and this three cheese blend hits all the right notes. Mozzarella brings the stretch fontina adds that buttery nutty richness and sharp cheddar provides the tang that prevents the sandwich from being too one dimensional. The proportions matter too too much cheddar overpowers the delicate pesto while too much mozzarella makes it bland.

The Bread That Makes The Difference

Sourdough isnt just about the tangy flavor its about structure and texture. The open crumb creates little pockets where pesto and cheese pool together creating intense bursts of flavor. Plus the sturdy exterior can withstand butter and heat without getting soggy or falling apart which is crucial when youre dealing with this much melting cheese.

Perfecting The Grill

Getting that golden exterior without burning the bread takes patience and the right temperature. I learned this the hard way after countless sandwiches with burnt edges and cold centers. The key is letting the pan heat properly then resisting the urge to crank up the heat when things seem to be taking too long.

  • Keep the butter at room temperature so it spreads smoothly without tearing the bread
  • Use a spatula to peek underneath occasionally rather than relying solely on timing since every pan heats differently
  • Let the sandwiches rest for that full minute after cooking to prevent that sad cheese spill when you slice
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Handle kitchen cleanup easily by disposing of food scraps, packaging, and cooking waste without leaks or odors.
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Two halves of a warm Sourdough Pesto Grilled Cheese stacked on a plate, ready to be enjoyed for lunch. Save to Pinterest
Two halves of a warm Sourdough Pesto Grilled Cheese stacked on a plate, ready to be enjoyed for lunch. | recipesbies.com

Theres something so satisfying about taking that first bite and hitting all the layers at once the crunch the creamy cheese the bright pesto. Simple food done right beats complicated any day of the week.

Answers to Recipe Questions

Can I make this sandwich ahead of time?

While this sandwich is best enjoyed fresh off the griddle, you can prepare the ingredients in advance. Assemble the sandwiches just before cooking to maintain the bread's integrity and ensure optimal cheese melting and crust formation.

What's the best way to get a crispy crust?

Use medium heat and cook for 3-4 minutes per side. Press gently with a spatula to ensure even contact with the griddle. Spreading softened butter on the outer bread surfaces helps achieve that golden, crispy exterior while the cheese melts inside.

Can I substitute the cheeses?

Absolutely. Gruyère, provolone, or fontina work beautifully as alternatives. Choose cheeses with good melting qualities and complementary flavors. A mix of mild and sharp varieties creates the best balance of richness and complexity.

Is homemade pesto better than store-bought?

Both work well. Homemade pesto offers fresher basil flavor and allows you to adjust ingredients for dietary needs, especially if you want to avoid nuts. Store-bought pesto is convenient and saves time while still delivering excellent flavor.

How can I make this vegan-friendly?

Use plant-based butter, dairy-free cheese alternatives, and verify your pesto is plant-based or make your own. Cashew-based or nutritional yeast options work well. The cooking technique remains the same—just monitor closely to ensure proper melting of your cheese substitute.

What bread works best besides sourdough?

While sourdough's tang complements the pesto beautifully, you can use ciabatta, focaccia, or thick-cut country bread. Avoid thin bread that may fall apart. Choose varieties with enough structure to hold the cheese and withstand pressing during grilling.

Sourdough Pesto Grilled Cheese

A rich twist on classic grilled cheese with thick sourdough, basil pesto, and a melty trio of cheeses grilled to golden perfection.

Prep duration
10 mins
Time to cook
10 mins
Overall time
20 mins
Published by Sophie Turner


Skill Level Easy

Cuisine Type American-Italian

Serves 2 Serving size

Dietary Details No meat included

What you need

Bread

01 4 slices thick-cut sourdough bread

Cheese

01 1/2 cup shredded mozzarella cheese
02 1/2 cup shredded fontina cheese
03 1/2 cup shredded sharp white cheddar cheese

Spreads & Condiments

01 3 tablespoons basil pesto
02 2 tablespoons unsalted butter, softened

How to Make It

Step 01

Butter the bread: Lay out sourdough slices and spread 1/2 tablespoon of softened butter on one side of each slice.

Step 02

Apply pesto and cheese: Flip bread over and spread approximately 1 tablespoon of basil pesto on the unbuttered side of two slices. Evenly distribute mozzarella, fontina, and cheddar cheese over the pesto-covered slices.

Step 03

Assemble sandwiches: Top pesto and cheese-laden slices with remaining bread slices, ensuring buttered side faces outward.

Step 04

Preheat cooking surface: Heat a large nonstick skillet or griddle over medium heat until evenly warmed.

Step 05

Grill sandwiches: Place assembled sandwiches in the skillet and cook 3-4 minutes per side, gently pressing with a spatula, until bread achieves golden-brown crispness and cheese melts completely.

Step 06

Rest and serve: Transfer sandwiches to a plate and allow 1 minute cooling time. Slice diagonally and serve immediately while warm.

Equipment You'll Need

  • Nonstick skillet or griddle
  • Spatula
  • Bread knife
  • Cheese grater

Allergy Details

Review all ingredients for allergens, and reach out to a healthcare pro if unsure.
  • Wheat from sourdough bread
  • Milk from cheese and butter
  • Tree nuts potentially present in pesto formulations

Nutrition info (by portion)

Nutrition info is for guidance. Please consult a medical expert if you need advice.
  • Total Calories: 480
  • Fat content: 29 g
  • Carbohydrate: 36 g
  • Protein content: 19 g